Article
A serotonin receptor gene (5HT1A) variant found in a Tourette's syndrome patient.
Biochemical and biophysical research communications - 27 Feb 1996
Lam S, Shen Y, Nguyen T, Messier T L, Brann M, Comings D, George S R, O'Dowd B F
Abstract excerpt
Serotonergic pathway disturbances have been implicated in neuropsychiatric disorders such as Tourette's syndrome (TS), substance abuse, and depression. In order to search for the presence of an association between these neuropsychiatric disorders and particular serotonin receptors isolated from t...
Topics
- Alcoholism
- Amino Acid Sequence
- Animals
- Base Sequence
- DNA Primers
- Depressive Disorder
- Genetic Variation
- Humans
- Models, Structural
- Molecular Sequence Data
- Polymerase Chain Reaction
- Polymorphism, Single-Stranded Conformational
- Protein Structure, Secondary
- Rats
- Receptors, Serotonin
- Receptors, Serotonin, 5-HT1
- Tourette Syndrome