Article
Association between harmful alcohol consumption behavior and dopamine transporter (DAT1) gene polymorphisms in a male Finnish population.
Psychiatric genetics - 1 Jun 2009
Lind Penelope A, Eriksson C J Peter, Wilhelmsen Kirk C
Abstract excerpt
BACKGROUND: Ethanol-induced dopamine (DA) release in the mesolimbic system may reinforce excessive alcohol intake and the progression of alcohol dependence. Within this reward system, the DA transporter (DAT1) plays a key role in the regulation of dopaminergic neurotransmission through presynaptic DA reuptake. OBJECTIVE: This study investigated whether DAT1 genetic variation was associated with either alcohol...
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