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Article

CD8+ T cells of Tc2 phenotype mediate a GVL effect and prevent marrow rejection.

Vox sanguinis - 1 Jan 1998

Fowler D H, Gress R E

Abstract excerpt

Donor T cells mediate both beneficial and detrimental immune reactions in the setting of allogeneic BMT (alloBMT). T cells mediate the GVL effect and prevent marrow rejection, but also induce GVHD. In an attempt to favorably influence the balance of these allogeneic responses, we have evaluated the effect of donor CD4+, Th1/Th2 and CD8+, Tc1/Tc2 functional T cell subsets in murine marrow transplantation models....

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Identifiers

PMID: 9704464
DOI: 10.1111/j.1423-0410.1998.tb05439.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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