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Article

Non-host-reactive donor CD8+ T cells of Tc2 phenotype potently inhibit marrow graft rejection.

Blood - 1 Jun 1998

Fowler D H, Whitfield B, Livingston M, Chrobak P, Gress R E

Abstract excerpt

Donor CD8+ T cells capable of host reactivity inhibit marrow graft rejection, but also generate graft-versus-host disease (GVHD). To evaluate whether the Tc1- and Tc2-type subsets of CD8 cells might inhibit rejection without host reactivity, we established an F1 into-parent murine bone marrow transplant model. Donor Tc1 and Tc2 cells were generated that preferentially secreted type I or type II cytokines; both...

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Identifiers

PMID: 9596648

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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