Article
Apolipoprotein E genotypes in sporadic early and late-onset Alzheimer's disease.
Archivum immunologiae et therapiae experimentalis - 1 Jan 1998
Kowalska A, Florczak J, Pruchnik-Wolińska D, Kraszewski A, Wender M
Abstract excerpt
Recent data have demonstrated that presence of apolipoprotein E (APOE) epsilon *4 allele is a major risk factor of Alzheimer's disease (AD). We determined the APOE genotypes in 64 patients with sporadic probable AD and 43 non-demented aged controls selected from Poznań region and the western part of Poland using the polymerase chain reaction (PCR) followed by the restriction fragment length polymorphism (RFLP)...
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