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Article

Ultra-ultra rapid cycling bipolar disorder is associated with the low activity catecholamine-O-methyltransferase allele.

Molecular psychiatry - 1 Jul 1998

Papolos D F, Veit S, Faedda G L, Saito T, Lachman H M

Abstract excerpt

Bipolar spectrum disorders are recurrent illnesses characterized by episodes of depression, hypomania, mania or the appearance of mixed states. Great variability is evident in the frequency of episode recurrence and duration. In addition to regular circannual episodes, a spectrum of cycle frequencies has been observed, from the classical rapid cycling (RC) pattern of four or more episodes per year, to those with...

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Source

Identifiers

PMID: 9702745
DOI: 10.1038/sj.mp.4000410

Genes

COMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Ultra-ultra rapid cycling bipolar disorder is associated with the low activity catecholamine-O-methyltransferase allele.PMID 9702745Read ↗

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Preliminary evidence of an association between bipolar disorder in females and the catechol-O-methyltransferase gene.Semantic proximity Read ↗

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