Ultra-ultra rapid cycling bipolar disorder is associated with the low activity catecholamine-O-methyltransferase allele.

doi:10.1038/sj.mp.4000410

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Article

Ultra-ultra rapid cycling bipolar disorder is associated with the low activity catecholamine-O-methyltransferase allele.

Molecular psychiatry - 1 Jul 1998

Papolos D F, Veit S, Faedda G L, Saito T, Lachman H M

Abstract excerpt

Bipolar spectrum disorders are recurrent illnesses characterized by episodes of depression, hypomania, mania or the appearance of mixed states. Great variability is evident in the frequency of episode recurrence and duration. In addition to regular circannual episodes, a spectrum of cycle frequen...

Topics

Adult
Age of Onset
Aged
Alleles
Bipolar Disorder
Catechol O-Methyltransferase
Female
Genetic Variation
Genotype
Humans
Male
Middle Aged
Polymorphism, Genetic

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