Rapid cycling in bipolar disorder: a systematic review.

Abstract excerpt

OBJECTIVE: THE long-term course of bipolar disorder is typified by recurring mood episodes of opposite polarity as well as mixed states. Rapid-cycling bipolar disorder refers to the presence of at least 4 mood episodes in the previous 12 months that meet the criteria for manic, hypomanic, or major depressive episode. The purpose of this study was to synthesize data regarding prevalence, clinical correlates, and...

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