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Article

[Characterization of ligand-dependent transactivation regions of the human vitamin D receptor].

Nihon rinsho. Japanese journal of clinical medicine - 1 Jul 1998

Nakajima S

Abstract excerpt

The 1,25-dihydroxyvitamin D receptor (VDR) belongs to the nuclear hormone receptor family. Mutational analysis revealed that the carboxyl-terminal region between leucine-417 and glutamic acid-420 of the human VDR is essential for the ligand-dependent transactivation. Mutant VDR at this AF-2 region exhibits only weak suppressive effect on the transactivation via the wild type receptor compared to the estrogen and...

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Source

Identifiers

PMID: 9702043

Genes

VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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[Characterization of ligand-dependent transactivation regions of the human vitamin D receptor].PMID 9702043Read ↗

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Novel N-Terminal Variant of Human VDRSemantic proximity Read ↗

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