Article
[Functional analysis of nuclear hormone receptors].
Nihon rinsho. Japanese journal of clinical medicine - 1 Jul 1998
Nagaya T, Seo H
Abstract excerpt
Nuclear hormone receptors are transcription factors which regulate gene transcription by lipophilic hormones. The functional domains such as transactivation, DNA binding, ligand binding and dimerization are mapped in the distinct region of the receptors. To analyze these functions, ligand binding assay, gel shift assay, transfection study, GST pull-down method, immunoprecipitation method, two hybrid system and...
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