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Article

Decreased bone mass and bone elasticity in mice lacking the transforming growth factor-beta1 gene.

Bone - 1 Aug 1998

Geiser A G, Zeng Q Q, Sato M, Helvering L M, Hirano T, Turner C H

Abstract excerpt

Transforming growth factor-beta1 (TGF-beta1) knockout (TGF-beta1(-/-)) mice were used to investigate the role of TGF-beta1 in postnatal bone development. Volumetric bone mineral density (BMD) and mineral content (BMC) in these mice and in their normal (TGF-beta1(+/+)) and heterozygous (TGF-beta1(+/-)) littermates were analyzed by quantitative computed tomography (pQCT). Analysis of the proximal tibial metaphysis...

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Source

Identifiers

PMID: 9701466
DOI: 10.1016/s8756-3282(98)00078-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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