Article
Transforming growth factor-beta1 to the bone.
Endocrine reviews - 1 Oct 2005
Janssens Katrien, ten Dijke Peter, Janssens Sophie, Van Hul Wim
Abstract excerpt
TGF-beta1 is a ubiquitous growth factor that is implicated in the control of proliferation, migration, differentiation, and survival of many different cell types. It influences such diverse processes as embryogenesis, angiogenesis, inflammation, and wound healing. In skeletal tissue, TGF-beta1 plays a major role in development and maintenance, affecting both cartilage and bone metabolism, the latter being the...
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