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Article

Congenital lack of COX-2 affects mechanical and geometric properties of bone in mice.

Calcified tissue international - 1 Oct 2003

Chen Q, Rho J Y, Fan Z, Laulederkind S J F, Raghow R

Abstract excerpt

We compared the mechanical properties of bones from mice lacking either a functional cycloxygenase-1 (C57BL6/DBA COX-1-/-; n = 9) or COX-2 (C57BL6/DBA COX-2-/-; n = 9) gene and wild type mice (C57BL6/DBA; n = 10). Twenty-eight right femora from 3-month-old male mice were used to determine bulk st...

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Identifiers

PMID: 12874706
DOI: 10.1007/s00223-002-0009-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12874706-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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