Article
Immune deficiencies due to defects in cytokine signaling.
Current allergy and asthma reports - 1 Sept 2003
Kelly John, Leonard Warren J
Abstract excerpt
Severe combined immunodeficiency (SCID) represents a syndrome comprising the most severe forms of inherited immunodeficiencies. Defects in cytokine signaling pathways can result in impaired development of lymphoid cells and/or defective functioning of these cells, and most cases of SCID result from defective signaling through the common cytokine receptor g chain (g(c)) or associated molecules and signaling...
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