Article
The histologic phenotypes of breast carcinoma occurring before age 40 years in women with and without BRCA1 or BRCA2 germline mutations: a population-based study.
Cancer - 1 Dec 1998
Armes J E, Egan A J, Southey M C, Dite G S, McCredie M R, Giles G G, Hopper J L, Venter D J
Abstract excerpt
BACKGROUND: Women with breast carcinoma diagnosed before age 40 years have a greater prevalence of germline BRCA1 and BRCA2 mutations than women with breast carcinoma diagnosed at older ages. Several recognizable histologic characteristics have been identified in breast carcinoma from studies of...
Topics
- Adult
- Age of Onset
- Apoptosis
- Australia
- Breast Neoplasms
- Female
- Genes, BRCA1
- Genes, Tumor Suppressor
- Germ-Line Mutation
- Humans
- Necrosis
- Phenotype
- Population Surveillance