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Article

Inherited BRCA2 mutation associated with high grade breast cancer.

Breast cancer research and treatment - 1 Jan 1998

Agnarsson B A, Jonasson J G, Björnsdottir I B, Barkardottir R B, Egilsson V, Sigurdsson H

Abstract excerpt

Inheritance is believed to play a major role in 5-10% of breast cancer. The breast cancer susceptibility genes BRCA1 and BRCA2 are estimated to account for more than half of these cases. Recent studies have suggested that breast cancers associated with BRCA1 germline mutations are of higher grade than sporadic cases. The purpose of this investigation was to determine if there are significant pathologic and...

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Source

Identifiers

PMID: 9497100
DOI: 10.1023/a:1005853022804

Genes

BRCA2
BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The pathology of familial breast cancer: The pre-BRCA1/BRCA2 era: historical perspectives.Semantic proximity Read ↗

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