Article
Overexpression of a neural-specific rho family GTPase, cRac1B, selectively induces enhanced neuritogenesis and neurite branching in primary neurons.
The Journal of cell biology - 10 Aug 1998
Albertinazzi C, Gilardelli D, Paris S, Longhi R, de Curtis I
Abstract excerpt
Rho family GTPases have been implicated in cytoskeletal reorganization during neuritogenesis. We have recently identified a new gene of this family, cRac1B, specifically expressed in the chicken developing nervous system. This GTPase was overexpressed in primary neurons to study the role of cRac1B in the development of the neuronal phenotype. Overexpression of cRac1B induced an increment in the number of neurites...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.