Article
Overexpression of a neural-specific rho family GTPase, cRac1B, selectively induces enhanced neuritogenesis and neurite branching in primary neurons.
The Journal of cell biology - 10 Aug 1998
Albertinazzi C, Gilardelli D, Paris S, Longhi R, de Curtis I
Abstract excerpt
Rho family GTPases have been implicated in cytoskeletal reorganization during neuritogenesis. We have recently identified a new gene of this family, cRac1B, specifically expressed in the chicken developing nervous system. This GTPase was overexpressed in primary neurons to study the role of cRac1...
Topics
- Actins
- Amino Acid Sequence
- Animals
- Binding Sites
- Cells, Cultured
- Chick Embryo
- Cytoskeleton
- GTP Phosphohydrolases
- GTP-Binding Proteins
- Neurites
- Neurons
- Neuropeptides
- Phenotype
- Retina
- Sequence Homology, Amino Acid
- rac GTP-Binding Proteins
- rac1 GTP-Binding Protein