Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Caveolin-1 inhibits neurite growth by blocking Rac1/Cdc42 and p21-activated kinase 1 interactions.

Neuroreport - 29 May 2006

Kang Min-Ji, Seo Jeong-Sun, Park Woong-Yang

Abstract excerpt

Growth factors such as basic fibroblast growth factors (bFGFs) could induce the differentiation of mouse neuroblastoma cells. We examine the effect of caveolin-1 on bFGF-induced differentiation of N2a cells. Caveolin-1 blocked the formation of neurites and the phosphorylation of Erk upon bFGF tre...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Caveolin 1
Share to cdc42 GTP-Binding Protein
Share to Central Nervous System

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fibroblast Growth Factor 2

Share to Neurites

Share to p21-Activated Kinases

Share to rac1 GTP-Binding Protein

Share to Up-Regulation

Source

Identifiers

PMID: 16708022
DOI: 10.1097/01.wnr.0000220139.83671.60

Genes

PAK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16708022-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Caveolin-1 inhibits neurite growth by blocking Rac1/Cdc42 and p21-activated kinase 1 interactions.PMID 16708022Read ↗

Reggies/flotillins regulate cytoskeletal remodeling during neuronal differentiation via CAP/ponsin and Rho GTPases.Semantic proximity Read ↗

Rap1 mediates sustained MAP kinase activation induced by nerve growth factor.Semantic proximity Read ↗

Caveolin-1 Up-regulation during Epithelial to Mesenchymal Transition Is Mediated by Focal Adhesion KinaseSemantic proximity Read ↗

Essential role of type I(alpha) phosphatidylinositol 4-phosphate 5-kinase in neurite remodeling.Semantic proximity Read ↗

Rac1-dependent actin filament organization in growth cones is necessary for beta1-integrin-mediated advance but not for growth on poly-D-lysine.Semantic proximity Read ↗

Cell biology of caveolae and its implication for clinical medicine.Semantic proximity Read ↗

Caveolin-1 enhances metastasis formation in a human model of embryonal rhabdomyosarcoma through Erk signaling cooperationSemantic proximity Read ↗

Regulation of neurite outgrowth in N1E-115 cells through PDZ-mediated recruitment of diacylglycerol kinase zeta.Semantic proximity Read ↗

Pharmacological Modulation of Neurite Outgrowth in Human Neural Progenitor Cells by Inhibiting Non-Muscle Myosin IISemantic proximity Read ↗

Rap1GAP interacts with RET and suppresses GDNF-induced neurite outgrowth.Semantic proximity Read ↗

PAK5, a new brain-specific kinase, promotes neurite outgrowth in N1E-115 cells.Semantic proximity Read ↗

Overexpression of a neural-specific rho family GTPase, cRac1B, selectively induces enhanced neuritogenesis and neurite branching in primary neurons.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.