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Article

Rac1-dependent actin filament organization in growth cones is necessary for beta1-integrin-mediated advance but not for growth on poly-D-lysine.

Journal of neurobiology - 1 Dec 1998

Kuhn T B, Brown M D, Bamburg J R

Abstract excerpt

The activity of filopodia and lamellipodia determines the advance, motility, adhesion, and sensory capacity of neuronal growth cones. The shape and dynamics of these highly motile structures originate from the continuous reorganization of the actin cytoskeleton in response to extracellular signals. The small GTPases, Rac1, Rho, and CDC42, regulate the organization of actin filament structures in nonneuronal...

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Source

Identifiers

PMID: 9858256
DOI: 10.1002/(sici)1097-4695(199812)37:4<524::aid-neu3>3.0.co;2-h

Genes

CDC42

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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