Article
Regulation of dendritic growth and remodeling by Rho, Rac, and Cdc42.
Neuron - 1 Sept 1997
Threadgill R, Bobb K, Ghosh A
Abstract excerpt
The acquisition of cell type-specific morphologies is a central feature of neuronal differentiation and has important consequences for nervous system function. To begin to identify the underlying molecular mechanisms, we have explored the role of Rho-related GTPases in the dendritic development of cortical neurons. Expression of dominant negative mutants of Rac or Cdc42, the Rho-inhibitory molecule C3...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
