Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

RA-RhoGAP, Rap-activated Rho GTPase-activating protein implicated in neurite outgrowth through Rho.

The Journal of biological chemistry - 23 Sept 2005

Yamada Tomohiro, Sakisaka Toshiaki, Hisata Shu, Baba Takeshi, Takai Yoshimi

Abstract excerpt

Rap1 and Rho small G proteins have been implicated in the neurite outgrowth, but the functional relationship between Rap1 and Rho in the neurite outgrowth remains to be established. Here we identified a potent Rho GTPase-activating protein (GAP), RA-RhoGAP, as a direct downstream target of Rap1 in the neurite outgrowth. RA-RhoGAP has the RA and GAP domains and showed GAP activity specific for Rho, which was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Size
Share to Cyclic AMP
Share to GTPase-Activating Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Guanosine Triphosphate

Share to Neurites

Share to rho GTP-Binding Proteins

Share to Tissue Distribution

Share to Two-Hybrid System Techniques

Source

Identifiers

PMID: 16014623
DOI: 10.1074/jbc.M504587200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

RA-RhoGAP, Rap-activated Rho GTPase-activating protein implicated in neurite outgrowth through Rho.PMID 16014623Read ↗

Rho and Ras GTPases in axon growth, guidance, and branching.Semantic proximity Read ↗

Rap1GAP interacts with RET and suppresses GDNF-induced neurite outgrowth.Semantic proximity Read ↗

The Inverse F-BAR Domain Protein srGAP2 Acts through srGAP3 to Modulate Neuronal Differentiation and Neurite Outgrowth of Mouse Neuroblastoma CellsSemantic proximity Read ↗

The Human Rho-GEF trio and its target GTPase RhoG are involved in the NGF pathway, leading to neurite outgrowth.Semantic proximity Read ↗

Diverse roles of Rho family GTPases in neuronal development, survival, and deathSemantic proximity Read ↗

Crosstalk between the Rho and Rab family of small GTPases in neurodegenerative disordersSemantic proximity Read ↗

Role of the Rho GTPase-activating protein RICS in neurite outgrowth.Semantic proximity Read ↗

Rho signaling research: history, current status and future directionsSemantic proximity Read ↗

p200 RhoGAP promotes cell proliferation by mediating cross-talk between Ras and Rho signaling pathways.Semantic proximity Read ↗

Sema4D-plexin-B1 implicated in regulation of dendritic spine density through RhoA/ROCK pathway.Semantic proximity Read ↗

What Is the Role of the Rho-ROCK Pathway in Neurologic Disorders?Semantic proximity Read ↗

Rac GTPases control axon growth, guidance and branching.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.