Contribution of the IL-2 and IL-10 genes to inflammatory bowel disease (IBD) susceptibility.

doi:10.1046/j.1365-2249.1998.00625.x

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Article

Contribution of the IL-2 and IL-10 genes to inflammatory bowel disease (IBD) susceptibility.

Clinical and experimental immunology - 1 Jul 1998

Parkes M, Satsangi J, Jewell D

Abstract excerpt

Although the importance of genetic susceptibility to IBD has been established by epidemiological studies, the genes involved remain poorly characterized. Important candidate genes include those encoding the immunoregulatory cytokines IL-2 and IL-10. The aim of this study was to assess the contrib...

Topics

Alleles
Chromosomes, Human, Pair 1
Chromosomes, Human, Pair 4
Colitis, Ulcerative
Crohn Disease
Disease Susceptibility
Genetic Linkage
Genotype
Humans
Inflammatory Bowel Diseases
Interleukin-10
Interleukin-2
Microsatellite Repeats

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