Article
Contribution of the IL-2 and IL-10 genes to inflammatory bowel disease (IBD) susceptibility.
Clinical and experimental immunology - 1 Jul 1998
Parkes M, Satsangi J, Jewell D
Abstract excerpt
Although the importance of genetic susceptibility to IBD has been established by epidemiological studies, the genes involved remain poorly characterized. Important candidate genes include those encoding the immunoregulatory cytokines IL-2 and IL-10. The aim of this study was to assess the contribution of the IL-2 and IL-10 genes to IBD susceptibility. One hundred and ninety-eight pairs of siblings with IBD were...
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