Article
Interleukin-10 (IL-10) genotypes in inflammatory bowel disease.
Tissue antigens - 1 Oct 1999
Tagore A, Gonsalkorale W M, Pravica V, Hajeer A H, McMahon R, Whorwell P J, Sinnott P J, Hutchinson I V
Abstract excerpt
Interleukin-10 (IL-10) is an anti-inflammatory cytokine. Its production in humans is under genetic control, and genotype defines high or low producers of this cytokine. This study addresses the hypothesis that idiopathic inflammatory bowel disease (IBD) patients are more likely to have the low IL-10 producer genotype and phenotype. DNA was extracted from blood cells of patients with Crohn's disease (CD) or with...
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