The effect of IL-10 genetic variation and interleukin 10 serum levels on Crohn's disease susceptibility in a New Zealand population.

doi:10.1016/j.humimm.2011.02.014

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Article

The effect of IL-10 genetic variation and interleukin 10 serum levels on Crohn's disease susceptibility in a New Zealand population.

Human immunology - 1 May 2011

Wang Alice H, Lam Wen-Jiun, Han Dug-Yeo, Ding Yaoyao, Hu Rong, Fraser Alan G, Ferguson Lynnette R, Morgan Angharad R

Abstract excerpt

Interleukin (IL)-10 has important effects in immunoregulation and inflammation, and previous studies have provided evidence for the involvement of IL-10 in the pathogenesis of Crohn's disease (CD). In this study, we investigated whether genetic variants of the IL-10 gene were associated with CD in a New Zealand population. Three single nucleotide polymorphisms (SNPs) in the promoter region of IL-10 (rs1800871,...

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PMID: 21354456
DOI: 10.1016/j.humimm.2011.02.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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