Article
Distinct C/EBP functions are required for eosinophil lineage commitment and maturation.
Genes & development - 1 Aug 1998
Nerlov C, McNagny K M, Döderlein G, Kowenz-Leutz E, Graf T
Abstract excerpt
Hematopoietic differentiation involves the commitment of multipotent progenitors to a given lineage, followed by the maturation of the committed cells. To study the transcriptional events controlling these processes, we have investigated the role of C/EBP proteins in lineage choice of multipotent...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- CCAAT-Enhancer-Binding Proteins
- Cell Differentiation
- Chickens
- DNA-Binding Proteins
- Eosinophils
- Gene Expression Regulation, Developmental
- Hematopoiesis
- Hematopoietic Stem Cells
- Models, Biological
- Molecular Sequence Data
- Nuclear Proteins
- Receptors, Estrogen
- Recombinant Fusion Proteins
- Transcriptional Activation
- Transfection