Article
Familial psoriasis and HLA-B: unambiguous support for linkage in 97 published families.
Human heredity - 1 Jan 2000
Leder R O, Mansbridge J N, Hallmayer J, Hodge S E
Abstract excerpt
The existence of a psoriasis susceptibility locus, PSORS1 (HUGO/GDB-approved symbol), in or near the HLA region of chromosome 6 is strongly supported by a lod score analysis of HLA-B and psoriasis in 97 families from 16 published datasets. Families included in the dataset represent all the psoriasis families with usable HLA data that we could find in the published literature through May 1997. The recombination...
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