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Article

Evidence for two psoriasis susceptibility loci (HLA and 17q) and two novel candidate regions (16q and 20p) by genome-wide scan.

Human molecular genetics - 1 Aug 1997

Nair R P, Henseler T, Jenisch S, Stuart P, Bichakjian C K, Lenk W, Westphal E, Guo S W, Christophers E, Voorhees J J, Elder J T

Abstract excerpt

In a 12.5 cM genome-wide scan for psoriasis susceptibility loci, recombination-based tests revealed linkage to the HLA region (Zmax = 3.52), as well as suggestive linkage to two novel regions: chromosome 16q (60-83.1 cM from pter, Zmax = 2.50), and chromosome 20p (7.5-25 cM from pter, Zmax = 2.62...

Topics

Adult
Alleles
Cell Line
Chromosome Mapping
Chromosomes, Human, Pair 16
Chromosomes, Human, Pair 17
Chromosomes, Human, Pair 20
Female
Genetic Linkage
Genetic Predisposition to Disease
HLA Antigens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Male

Psoriasis

Recombination, Genetic

Source

Identifiers

PMID: 9259283
DOI: 10.1093/hmg/6.8.1349

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9259283-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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