Article
p53 and follow-up of colorectal adenocarcinomas.
Digestive diseases and sciences - 1 Jul 1998
Polge A, Bourgaux J F, Bancel E, Pignodel C, Boyer J C, Poirey S, de Bornier B M, Balmes J L, Bali J P
Abstract excerpt
Circulating p53 antibodies (ELISA method), p53 genetic alterations (SSCP), and protein overexpression (immunohistochemistry) were studied in 41 patients with colorectal adenocarcinomas and 10 control patients. Carcinoembryonic antigen (CEA) and carbohydrate antigen 19.9 (CA 19-9) were evaluated i...
Topics
- Adenocarcinoma
- Aged
- Aged, 80 and over
- Biomarkers, Tumor
- Case-Control Studies
- Colorectal Neoplasms
- DNA, Neoplasm
- Enzyme-Linked Immunosorbent Assay
- Female
- Follow-Up Studies
- Genes, p53
- Humans
- Male
- Middle Aged
- Mutation
- Polymerase Chain Reaction
- Polymorphism, Single-Stranded Conformational
- Tumor Suppressor Protein p53