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Article

Regulation of expression of human SP-A1 and SP-A2 genes in fetal lung explant culture.

Biochimica et biophysica acta - 16 Jun 1998

Karinch A M, Deiter G, Ballard P L, Floros J

Abstract excerpt

Human pulmonary surfactant protein A (SP-A) is genetically complex and its regulation may also be complex, reflecting genotypic variability. Fetal lung explants were used to study the regulation of the SP-A genes, SP-A1 and SP-A2, by dexamethasone, interferon, gamma (IFN gamma), cyclic 3',-5' adenosine monophosphate (cAMP), and tumor necrosis factor alpha (TNF alpha). For comparison, the mRNA levels of surfactant...

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PMID: 9689918
DOI: 10.1016/s0167-4781(98)00047-5

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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