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Article

Genetic complexity of the human surfactant-associated proteins SP-A1 and SP-A2.

Gene - 1 Dec 2013

Silveyra Patricia, Floros Joanna

Abstract excerpt

Pulmonary surfactant protein A (SP-A) plays a key role in innate lung host defense, in surfactant-related functions, and in parturition. In the course of evolution, the genetic complexity of SP-A has increased, particularly in the regulatory regions (i.e. promoter, untranslated regions). Although most species have a single SP-A gene, two genes encode SP-A in humans and primates (SFTPA1 and SFTPA2). This may...

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Source

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Identifiers

PMID: 23069847
DOI: 10.1016/j.gene.2012.09.111
PMCID: PMC3570704

Genes

SFTPA1
SFTPA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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