Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Differential Regulation of Human Surfactant Protein A Genes, SFTPA1 and SFTPA2, and Their Corresponding Variants.

Frontiers in immunology - 1 Jan 2021

Floros Joanna, Tsotakos Nikolaos

Abstract excerpt

The human SFTPA1 and SFTPA2 genes encode the surfactant protein A1 (SP-A1) and SP-A2, respectively, and they have been identified with significant genetic and epigenetic variability including sequence, deletion/insertions, and splice variants. The surfactant proteins, SP-A1 and SP-A2, and their corresponding variants play important roles in several processes of innate immunity as well in surfactant-related...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to 5' Untranslated Regions
Share to Base Sequence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Variation

Share to Immunity, Innate

Share to Pulmonary Surfactant-Associated Protein A

Share to Sequence Homology, Nucleic Acid

Share to Transcriptome

Source

Open in PubMed Open full text

Identifiers

PMID: 34917085
DOI: 10.3389/fimmu.2021.766719
PMCID: PMC8669794

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Differential Regulation of Human Surfactant Protein A Genes, SFTPA1 and SFTPA2, and Their Corresponding Variants.PMID 34917085Read ↗

Human Surfactant Protein SP-A1 and SP-A2 Variants Differentially Affect the Alveolar Microenvironment, Surfactant Structure, Regulation and Function of the Alveolar Macrophage, and Animal and Human Survival Under Various Conditions.Semantic proximity Read ↗

Genetic complexity of the human surfactant-associated proteins SP-A1 and SP-A2.Semantic proximity Read ↗

Genetic Complexity of the Human Innate Host Defense Molecules, Surfactant Protein A1 (SP-A1) and SP-A2Impact on FunctionSemantic proximity Read ↗

Genetic Diversity of Human SP-A, a Molecule with Innate host Defense and Surfactant-Related Functions; Characteristics, Primary Function, and Significance.Semantic proximity Read ↗

Human surfactant protein A (SP-A) variants: why so many, why such a complexity?Semantic proximity Read ↗

Genetic variant associations of human SP-A and SP-D with acute and chronic lung injury.Semantic proximity Read ↗

Surfactant protein A: A key player in lung homeostasisSemantic proximity Read ↗

5' splicing and allelic variants of the human pulmonary surfactant protein A genes.Semantic proximity Read ↗

Air pollution and epigenetics: effects on SP-A and innate host defence in the lungSemantic proximity Read ↗

Surfactant proteins as genetic determinants of multifactorial pulmonary diseases.Semantic proximity Read ↗

Surfactant protein disorders in childhood interstitial lung disease.Semantic proximity Read ↗

Altered Surfactant Protein Gene Expression in Peripheral Blood Is Associated with COVID-19 Disease SeveritySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.