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Article

Genetic association of Ctla-4 to myasthenia gravis with thymoma.

Journal of neuroimmunology - 1 Aug 1998

Huang D, Liu L, Norén K, Xia S Q, Trifunovic J, Pirskanen R, Lefvert A K

Abstract excerpt

Cytotoxic T lymphocyte associated antigen-4 (CTLA-4) plays a pivotal role in downregulating both the cellular and the humoral response by suppressing ongoing responses of activated T cells. Our earlier study showed that genetic variations in interleukin-1 genes confer susceptibility to myasthenia gravis, especially in patients having the lowest risk from major histocompatibility complex genes. Here we describe an...

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Source

Identifiers

PMID: 9688341
DOI: 10.1016/s0165-5728(98)00119-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic association of Ctla-4 to myasthenia gravis with thymoma.PMID 9688341Read ↗

[Studies on the genetic pathogenesis of myasthenia gravis caused by CTLA-4 gene polymorphism].Semantic proximity Read ↗

Association of CTLA-4 polymorphisms with increased risks of myasthenia gravis.Semantic proximity Read ↗

A CTLA4high genotype is associated with myasthenia gravis in thymoma patients.Semantic proximity Read ↗

CDS1 and promoter single nucleotide polymorphisms of the CTLA-4 gene in human myasthenia gravis.Semantic proximity Read ↗

Recent advances in genetic predisposition of myasthenia gravis.Semantic proximity Read ↗

Polygenic disease associations in thymomatous myasthenia gravis.Semantic proximity Read ↗

GENOMIC AND EPIGENOMIC PREDICTORS FOR VARIOUS CLINICAL PHENOTYPES OF MYASTHENIA GRAVIS.Semantic proximity Read ↗

CTLA4 variants and haplotype contribute genetic susceptibility to myasthenia gravis in northern Chinese population.Semantic proximity Read ↗

Association of the DNMT3B -579G>T polymorphism with risk of thymomas in patients with myasthenia gravis.Semantic proximity Read ↗

Elucidating genetic backgrounds of myasthenia gravis in Japanese by genome-wide association studies and multi-omics analyses of thymoma.Semantic proximity Read ↗

Linkage of HLA to myasthenia gravis and genetic heterogeneity depending on anti-titin antibodies.Semantic proximity Read ↗

Gene Polymorphisms for Both Auto-antigen and Immune-Modulating Proteins Are Associated with the Susceptibility of Autoimmune Myasthenia Gravis.Semantic proximity Read ↗

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