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GENOMIC AND EPIGENOMIC PREDICTORS FOR VARIOUS CLINICAL PHENOTYPES OF MYASTHENIA GRAVIS.

Wiadomosci lekarskie (Warsaw, Poland : 1960) - 1 Jan 2021

Klimova Elena M, Drozdova Larisa A, Lavinskaya Elena V, Minukhin Dmitriy V, Kudrevych Iryna O, Kudrevych Oleksandr M

Abstract excerpt

OBJECTIVE: The aim: To evaluate the relationship of certain alleles of HLA class II leukocyte antigens and the profile of antibodies to various subunits of nicotinic acetylcholine receptors (nAChR), the level of Treg lymphocytes and the serum concentration of anti-inflammatory IL-10 for various clinical myasthenia gravis phenotypes. PATIENTS AND METHODS: Materials and methods: We examined 217 patients with...

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PMID: 33813453

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