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Article

CTLA4 variants and haplotype contribute genetic susceptibility to myasthenia gravis in northern Chinese population.

PloS one - 1 Jan 2014

Sun Liang, Meng Yunxiao, Xie Yanchen, Zhang Hua, Zhang Zheng, Wang Xiaoxia, Jiang Bin, Li Wei, Li Yao, Yang Ze

Abstract excerpt

BACKGROUND: Cytotoxic T lymphocyte-associated antigen-4 (CTLA4), a critical negative regulator of the T-cell response, has been considered a candidate for many autoimmune diseases. Evidence from Caucasians supported a genetic predisposition of CTLA4 to myasthenia gravis (MG), but the contribution...

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Identifiers

PMID: 25003519
DOI: 10.1371/journal.pone.0101986
PMCID: PMC4086970

Genes

CTLA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25003519-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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