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Article

Gene Polymorphisms for Both Auto-antigen and Immune-Modulating Proteins Are Associated with the Susceptibility of Autoimmune Myasthenia Gravis.

Molecular neurobiology - 1 Aug 2017

Li Hai-Feng, Hong Yu, Zhang Xu, Xie Yanchen, Skeie Geir Olve, Hao Hong-Jun, Gilhus Nils Erik, Liang Bing, Yue Yao-Xian, Zhang Xian-Jun, Gao Xiang, Wang Qi, Gao Zhe, Ding Xiao-Jun, Song Min

Abstract excerpt

Myasthenia gravis (MG) is an antibody-mediated autoimmune disease against antigens at the neuromuscular junction. Both genetic and environmental factors contribute to the susceptibility of MG. We undertook a case-control study to explore the contribution of genes of the auto-antigen and immune-modulating proteins in the pathogenesis of MG. We enrolled 389 adult MG patients and 487 healthy controls. Eighteen SNPs...

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Source

Identifiers

PMID: 27501803
DOI: 10.1007/s12035-016-0024-y

Genes

CHRNA1
AIRE
PTPN22

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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