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Article

Association of CTLA-4 polymorphisms with increased risks of myasthenia gravis.

Annals of human genetics - 1 Nov 2018

Li Fang, Yuan Wuzhou, Wu Xiushan

Abstract excerpt

Myasthenia gravis (MG) is considered to be a kind of autoimmune disorder resulting from dysfunction of neuromuscular transmission caused by autoantibodies against the nicotinic acetylcholine receptors. A number of studies have identified Cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) as a candidate gene for MG. Several recent reports have indicated that single nucleotide polymorphisms (SNPs) of CTLA-4,...

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PMID: 30009380
DOI: 10.1111/ahg.12262

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