Article
Examination of the oncogenic potential of H19 gene in HeLa x normal human fibroblast hybrid cells.
International journal of oncology - 1 Jul 2001
Tsujimoto H, Nishizuka S, Redpath L J, Stanbridge E J
Abstract excerpt
Fusion of tumorigenic HeLa cells with human skin fibroblasts results in chromosomally stable non-tumorigenic hybrids. The studies of rare spontaneous tumorigenic segregants from the non-tumorigenic hybrid have implicated the loss of one copy of human fibroblast chromosome 11 with concomitant re-expression of tumorigenicity. In a previous study of differential display screening, we reported the...
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