Enhanced liver cell mutations in trematode-infected Big Blue transgenic mice.

doi:10.1016/s0027-5107(98)00049-9

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Article

Enhanced liver cell mutations in trematode-infected Big Blue transgenic mice.

Mutation research - 25 May 1998

Gentile J M, Gentile G J, Nannenga B, Johnson M, Blankespoor H, Montero R

Abstract excerpt

Parasite infections in humans have long been associated with specific types of cancers. Schistosoma hematobium is a known inducer of urinary bladder cancer, Helicobacter pylori is a gastric carcinogen, and hepatitis B virus and Opisthorchis viverrini are causative agents of liver cell cancers. An...

Topics

Animals
Bacterial Proteins
Coliphages
DNA Mutational Analysis
DNA, Helminth
Escherichia coli Proteins
Fasciola hepatica
Fascioliasis
Lac Repressors
Liver
Male
Mice
Mice, Inbred C57BL
Mice, Transgenic
Mutation
Repressor Proteins
Transgenes

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