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Complete and overlapping congenics proving the existence of a quantitative trait locus for blood pressure on Dahl rat chromosome 17.

Physiological genomics - 21 Mar 2005

Grondin Myrian, Eliopoulos Vasiliki, Lambert Raphaelle, Deng Yishu, Ariyarajah Anita, Moujahidine Myriam, Dutil Julie, Charron Sophie, Deng Alan Y

Abstract excerpt

Linkage studies suggested that a quantitative trait locus (QTL) for blood pressure (BP) was present in a region on chromosome 17 (Chr 17) of Dahl salt-sensitive (DSS) rats. A subsequent congenic strain targeting this QTL, however, could not confirm it. These conflicting results called into question the validity of localization of a QTL by linkage followed by the use of a congenic strain made with an incomplete...

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PMID: 15632271
DOI: 10.1152/physiolgenomics.00275.2004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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