Mutations of the STK11 gene in sporadic gastric carcinoma.

Article

Mutations of the STK11 gene in sporadic gastric carcinoma.

International journal of oncology - 1 Sept 1998

Park W S, Moon Y W, Yang Y M, Kim Y S, Kim Y D, Fuller B G, Vortmeyer A O, Fogt F, Lubensky I A, Zhuang Z

Abstract excerpt

Gastric carcinoma may occur sporadically or in association with hereditary diseases, such as Peutz-Jehgers syndrome (PJS). The PJS gene (named STK11 or LKB1) was mapped to 19p13.3 and recently cloned. Germ-line mutations of the gene have been detected in familial PJS patients and are predicted to...

Topics

Gene Expression Regulation, Neoplastic
Humans
Mutation
Peutz-Jeghers Syndrome
Stomach Neoplasms

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