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Article

LKB1 somatic mutations in sporadic tumors.

The American journal of pathology - 1 Mar 1999

Avizienyte E, Loukola A, Roth S, Hemminki A, Tarkkanen M, Salovaara R, Arola J, Bützow R, Husgafvel-Pursiainen K, Kokkola A, Järvinen H, Aaltonen L A

Abstract excerpt

Germline mutations of LKB1/Peutz-Jeghers syndrome gene predispose carriers to hamartomatous polyposis of the gastrointestinal tract as well as to cancer of different organ systems. Although Peutz-Jeghers syndrome patients frequently present with neoplasms of the colon, stomach, small intestine, p...

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Share to Amino Acid Substitution
Share to AMP-Activated Protein Kinase Kinases
Share to DNA, Neoplasm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neoplasms

Share to Polymorphism, Genetic

Share to Polymorphism, Single-Stranded Conformational

Share to Protein Serine-Threonine Kinases

Share to Tumor Cells, Cultured

Source

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Identifiers

PMID: 10079245
DOI: 10.1016/S0002-9440(10)65314-X
PMCID: PMC1868601

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-10079245-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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