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Article

A novel mutation in STK11 gene is associated with Peutz-Jeghers syndrome in Chinese patients.

BMC medical genetics - 14 Dec 2011

Wang Zhiqing, Chen Yulan, Wu Baoping, Zheng Haoxuan, He Jiman, Jiang Bo

Abstract excerpt

BACKGROUND: Peutz-Jeghers syndrome (PJS) is caused by mutations in the tumor suppressor gene, STK11, and is characterized by gastrointestinal hamartomas, melanin spots on the lips, and an increased risk of developing cancer. METHODS: Blood samples were collected from two unrelated Chinese PJS families totaling 20 individuals (9 male and 11 females), including 6 PJS patients. The entire coding region of the STK11...

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Source

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Identifiers

PMID: 22168747
DOI: 10.1186/1471-2350-12-161
PMCID: PMC3297525

Genes

STK11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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