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Article

Somatic mutations in the STK11/LKB1 gene are uncommon in rare gynecological tumor types associated with Peutz-Jegher's syndrome.

The American journal of pathology - 1 Jan 2000

Connolly D C, Katabuchi H, Cliby W A, Cho K R

Abstract excerpt

Peutz-Jegher's syndrome (PJS) is a rare autosomal dominant disorder characterized by mucocutaneous pigmentation, hamartomatous polyposis, and predisposition to benign and malignant tumors of the gastrointestinal tract, breast, ovary, uterine cervix, and testis. Germline-inactivating mutations in one allele of the STK11/LKB1 gene at chromosome 19p13.3 have been found in most PJS patients. Although ovarian sex cord...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genital Neoplasms, Female

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Source

Open in PubMed Open full text

Identifiers

PMID: 10623683
DOI: 10.1016/S0002-9440(10)64735-9
PMCID: PMC1868646

Genes

STK11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Somatic mutations in the STK11/LKB1 gene are uncommon in rare gynecological tumor types associated with Peutz-Jegher's syndrome.PMID 10623683Read ↗

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