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Article

Germline and somatic mutations of the STK11/LKB1 Peutz-Jeghers gene in pancreatic and biliary cancers.

The American journal of pathology - 1 Jun 1999

Su G H, Hruban R H, Bansal R K, Bova G S, Tang D J, Shekher M C, Westerman A M, Entius M M, Goggins M, Yeo C J, Kern S E

Abstract excerpt

Peutz-Jeghers syndrome (PJS) is an autosomal-dominant disorder characterized by hamartomatous polyps in the gastrointestinal tract and by pigmented macules of the lips, buccal mucosa, and digits. Less appreciated is the fact that PJS also predisposes patients to an increased risk of gastrointestinal cancer, and pancreatic cancer has been reported in many PJS patients. It was recently shown that germline mutations...

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Source

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Identifiers

PMID: 10362809
DOI: 10.1016/S0002-9440(10)65440-5
PMCID: PMC1866632

Genes

STK11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

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Germline and somatic mutations of the STK11/LKB1 Peutz-Jeghers gene in pancreatic and biliary cancers.PMID 10362809Read ↗

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