Article
Relative frequency and morphology of cancers in STK11 mutation carriers.
Gastroenterology - 1 Jun 2004
Lim Wendy, Olschwang Sylviane, Keller Josbert J, Westerman Anne Marie, Menko Fred H, Boardman Lisa A, Scott Rodney J, Trimbath Jill, Giardiello Francis M, Gruber Stephen B, Gille Johan J P, Offerhaus G Johan A, de Rooij Felix W M, Wilson J H Paul, Spigelman Allan D, Phillips Robin K S, Houlston Richard S
Abstract excerpt
BACKGROUND & AIMS: There is limited data on the spectrum and risk for cancer associated with germline serine/threonine protein kinase 11 (STK11) mutations that cause Peutz-Jeghers syndrome (PJS). METHODS: We analyzed the incidence of cancer in 240 individuals with PJS possessing germline mutation...
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