Article
Vascular endothelial growth factor and nitric oxide synthase expression in human lung cancer and the relation to p53.
British journal of cancer - 1 Jul 1998
Ambs S, Bennett W P, Merriam W G, Ogunfusika M O, Oser S M, Khan M A, Jones R T, Harris C C
Abstract excerpt
Vascular endothelial growth factor (VEGF) expression and mutations of cancer-related genes increase with cancer progression. This correlation suggests the hypothesis that oncogenes and tumour suppressors regulate VEGF, and a significant correlation between p53 alteration and increased VEGF expression in human lung cancer was reported recently. To further examine this hypothesis, we analysed VEGF protein...
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