Vascular endothelial growth factor and nitric oxide synthase expression in human lung cancer and the relation to p53.

doi:10.1038/bjc.1998.470

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Article

Vascular endothelial growth factor and nitric oxide synthase expression in human lung cancer and the relation to p53.

British journal of cancer - 1 Jul 1998

Ambs S, Bennett W P, Merriam W G, Ogunfusika M O, Oser S M, Khan M A, Jones R T, Harris C C

Abstract excerpt

Vascular endothelial growth factor (VEGF) expression and mutations of cancer-related genes increase with cancer progression. This correlation suggests the hypothesis that oncogenes and tumour suppressors regulate VEGF, and a significant correlation between p53 alteration and increased VEGF expres...

Topics

Carcinoma, Small Cell
Carcinoma, Squamous Cell
Endothelial Growth Factors
Genes, p53
Genes, ras
Humans
Lung Neoplasms
Lymphokines
Mutation
Nitric Oxide Synthase
Nitric Oxide Synthase Type II
Vascular Endothelial Growth Factor A
Vascular Endothelial Growth Factors

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Identifiers

PMID: 9683299
DOI: 10.1038/bjc.1998.470
PMCID: PMC2062907

Genes

NOS1
NOS2
NOS3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9683299-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.