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Article

The role of endothelial nitric oxide synthase gene polymorphisms in patients with lung cancer.

The clinical respiratory journal - 1 Oct 2020

Koçer Canan, Benlier Necla, Balci Sibel Oğuzkan, Pehlivan Sacide, Şanli Maruf, Nacak Muradiye

Abstract excerpt

OBJECTIVES: Lung cancer is a disease characterized by uncontrolled cell growth in the lung tissues. The most common causes of lung cancer include smoking, exposure to radon gas, asbestos, environmental pollutants as well as genetic factors. Nitric oxide (NO) has potential mutagenic and carcinogenic activity and may play an important role in lung cancer. Endothelial NO, synthesized from L-arginine by endothelial...

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PMID: 32568451
DOI: 10.1111/crj.13228

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