Article
Effect of green tea on p53 mutation distribution in ultraviolet B radiation-induced mouse skin tumors.
Carcinogenesis - 1 Jul 1998
Liu Q, Wang Y, Crist K A, Wang Z Y, Lou Y R, Huang M T, Conney A H, You M
Abstract excerpt
In the present study, administration of green tea to SKH-1 mice, via the drinking fluid, was found to significantly reduce the incidence and volume of ultraviolet B (UVB) radiation-induced skin tumors. Thirty-six skin tumors induced by UVB and 32 skin tumors induced by UVB, in mice treated with g...
Topics
- Animals
- Anticarcinogenic Agents
- Carcinoma, Large Cell
- Carcinoma, Squamous Cell
- Codon
- Exons
- Female
- Genes, p53
- Immunohistochemistry
- Mice
- Mice, Hairless
- Mutation
- Neoplasms, Radiation-Induced
- Polymerase Chain Reaction
- Skin Neoplasms
- Tea
- Tumor Suppressor Protein p53
- Ultraviolet Rays