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Article

p53 mutations in cutaneous lesions induced in the hairless mouse by a solar ultraviolet light simulator.

Molecular carcinogenesis - 1 Jul 1998

Queille S, Seite S, Tison S, Medaisko C, Drougard C, Fourtanier A, Sarasin A, Daya-Grosjean L

Abstract excerpt

We investigated skin lesions induced in hairless SKH:HR1 mice by chronic exposure to a solar ultraviolet light (UV) simulator for alterations of the p53 gene in conserved domains. Mutations of exons 5-8 of the p53 gene in skin lesions were screened in 31 benign skin lesions (hyperplasias), 25 precancerous skin lesions (keratoacanthomas), and 25 malignant skin lesions (squamous cell carcinomas; SCC) by polymerase...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9688142
DOI: 10.1002/(sici)1098-2744(199807)22:3<167::aid-mc4>3.0.co;2-i

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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