Article
Identification and characterization of the multiple endocrine neoplasia type 1 (MEN1) gene.
Journal of internal medicine - 1 Jun 1998
Guru S C, Manickam P, Crabtree J S, Olufemi S E, Agarwal S K, Debelenko L V
Abstract excerpt
For nearly a decade since the mapping of the multiple endocrine neoplasia type 1 (MEN1) locus to 11q13 and the suggestion that it is a tumour suppressor gene, efforts have been made to identify the gene responsible for this familial cancer syndrome. Recently, we have identified the MEN1 gene by t...
Topics
- Amino Acid Sequence
- Base Sequence
- Chromosomes, Human, Pair 11
- Cloning, Molecular
- Genetic Linkage
- Genetic Markers
- Haplotypes
- Humans
- Loss of Heterozygosity
- Molecular Sequence Data
- Multiple Endocrine Neoplasia Type 1
- Mutation