Article
Identification of the multiple endocrine neoplasia type 1 (MEN1) gene. The European Consortium on MEN1.
Human molecular genetics - 1 Jul 1997
Lemmens I, Van de Ven W J, Kas K, Zhang C X, Giraud S, Wautot V, Buisson N, De Witte K, Salandre J, Lenoir G, Pugeat M, Calender A, Parente F, Quincey D, Gaudray P, De Wit M J, Lips C J, Höppener J W, Khodaei S, Grant A L, Weber G, Kytölä S, Teh B T, Farnebo F, Thakker R V
Abstract excerpt
Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder characterised by tumours of the parathyroids, pancreas and anterior pituitary that represents one of the familial cancer syndromes. The MEN1 locus has been previously localised to chromosome 11q13, and a <300 kb gene-rich region flanked centromerically by PYGM and telomerically by D11S1783 defined by combined meiotic and tumour deletion...
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